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目的:总结系统性红斑狼疮(SLE)并急性腹痛的临床特点及诊断和治疗体会。方法:对15例有急性腹痛的SLE患者的临床资料进行回顾性分析。结果:15例患者中4例以急腹症为首发表现,11例见于SLE的不同的治疗阶段。临床上表现为急性腹膜炎、麻痹性肠梗阻、急性胰腺炎、缺血性肠梗死等。给予大剂量肾上腺皮质激素和(或)细胞毒性药物治疗的10例患者病情好转,给予常规肾上腺皮质激素治疗的4例有3例死亡。结论:SLE并急性腹痛可发生于SLE病程中的任何时期,有多种临床表现形式,其病情危重,病死率较高,应用大剂量肾上腺皮质激素和(或)细胞毒性药物常能迅速缓解症状,同时预防及控制感染可改善预后。
Objective: To summarize the clinical features, diagnosis and treatment of systemic lupus erythematosus (SLE) and acute abdominal pain. Methods: The clinical data of 15 SLE patients with acute abdominal pain were retrospectively analyzed. Results: Four of the 15 patients presented with acute abdomen as the first manifestation. Eleven patients were found in different stages of SLE. Clinical manifestations of acute peritonitis, paralytic ileus, acute pancreatitis, ischemic ileus and so on. Ten patients given high-dose adrenocorticotropic hormone and / or cytotoxic drugs improved in condition, and three of the four patients who received conventional adrenal cortical hormone therapy died. Conclusions: SLE with acute abdominal pain may occur at any stage during the course of SLE. There are many clinical manifestations, its critical condition, high mortality, the application of high doses of adrenocorticotropic hormone and (or) cytotoxic drugs can often quickly relieve symptoms , While preventing and controlling infection can improve the prognosis.