自本世纪初Ehrlich提出魔弹概念以来,人们探索把化疗药物、放射核素及毒素与抗体联接,使其能特异性杀伤肿瘤细胞。除抗体外,已探索用作载体的尚有脂质体、激素、刀豆素A、碘化油等。传统的抗肿瘤药物因特异性差、伤及正常骨髓细胞、肝细胞等增殖旺盛的细胞导致严重毒副作用而 Since Ehrlich introduced the magic bullet concept at the beginning of this century, people have explored linking chemotherapy drugs, radionuclides and toxins with antibodies to specifically kill tumor cells. In addition to antibodies, liposomes, hormones, concanavalin A, iodized oil, etc. have been explored as carriers. Traditional anti-tumor drugs cause severe toxic side effects due to poor specificity and damage to proliferative cells such as normal bone marrow cells and hepatocytes.