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目的：评价１，６－二磷酸果糖治疗慢性肺心病急性发作期的疗效。方法：治疗组７６例（男性４２例，女性３４例，年龄６３±ｓ８ａ），在用控制感染、祛痰、吸氧、平喘等治疗基础（常规疗法）上加用１，６－二磷酸果糖５ｇ静脉滴注，ｂｉｄ，７ｄ为一个疗程。另设对照组６２例（男性３４例，女性２８例；年龄６１±７ａ），仅用常规疗法，７ｄ为一个疗程。结果：前者总有效率８３％，后者５５％，差异非常显著（Ｐ＜０．０１）；前者动脉血气分析与血液流变学均显著改善（Ｐ＜０．０１），后者改善不明显（Ｐ＞０．０５）。未见不良反应。结论：加用１，６－二磷酸果糖疗效满意。
Objective: To evaluate the efficacy of 1,6-fructose in the treatment of acute episode of chronic pulmonary heart disease. Methods: The treatment group of 76 patients (42 males and 34 females, age 63 ± s8a), with the control of infection, expectorant, oxygen, asthma and other treatment based (conventional therapy) plus 1,6-diphosphate Fructose 5g intravenous infusion, bid, 7d for a course of treatment. Another control group of 62 patients (34 males and 28 females; age 61 ± 7a), only conventional therapy, 7d for a course of treatment. Results: The former had a total effective rate of 83%, while the latter 55%, the difference was very significant (P <0.01); the former arterial blood gas analysis and hemorheology were significantly improved (P <0.01), while the latter did not improve significantly (P> 0.05). No adverse reactions. Conclusion: The effect of adding fructose-1,6-diphosphate is satisfactory.