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近年来耐氯霉素伤寒菌株日益增多,造成治疗效果的减退,退热时间延长,甚至治疗失败;加之氯霉素有对骨髓抑制等副作用,更加限制其临床应用,诺氟沙星是新合成的第三代喹诺酮类抗菌药,它具有抗菌谱广,活性强,口服耐受性好,副作用发生率少而轻等特点。本文就诺氟沙星治疗1990年6～12月我科收住院的29例耐氯霉素伤寒病人情况进行了分析,29例病人男女各为15和14例,年龄3～54岁,平均33.2岁,诺氟沙星用量
In recent years, increasing resistance to chloramphenicol typhoid strains, resulting in the reduction of treatment, antipyretics, prolonged or even failed treatment; coupled with chloramphenicol on bone marrow suppression and other side effects, more limited its clinical application, norfloxacin is a new synthesis The third generation of quinolone antibacterial drugs, which has broad antibacterial spectrum, activity, oral tolerance, side effects and less incidence of mild characteristics. In this paper, 29 cases of chloramphenicol-resistant typhoid patients admitted to our department from June to December 1990 were analyzed. The 29 patients were 15 and 14 male and female, aged from 3 to 54 years (mean, 33.2%) Years old, norfloxacin dosage