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[目的]探讨早期脑梗死后抑郁症(PSD)患者梗死灶部位分布情况及其相关性.[方法]选择2008年3月至2017年8月本院神经内科收治的78例脑梗死患者,根据其是否存在抑郁将其分为 PSD组(n =40)和无抑郁症组(PSND组,n=38).所有患者均行 MRI扫描,分析两组脑梗死灶分布部位,并分析脑梗死灶分布部位与PSD发生的相关性.[结果]PSD 组梗死灶位于额颞顶叶皮质区、枕叶皮质区、脑干及小脑所占比例显著高于PSND组,差异具有统计学意义(P 枕叶皮质区>左额极距离>多发性梗死>海马杏仁核>左额叶>脑后部>右额叶>右额极距离>放射冠区>脑前部>基底核区.[结论]当脑梗死灶位于脑干及小脑、额颞顶枕叶皮质区以及病灶与左额极距离小等情况时易出现早期PSD,提示早期PSD与梗死灶部位具有一定的相关性.“,”[Objective]To investigate the distribution of infarct location in patients with early PSDs after early cere-bral infarction and its correlation.[Methods]From March 2008 to August 2017,78 patients with cerebral infarction were selected and divided into PSD group (n =40)and non-depression group (n =38,PSND).All patients were scanned with MRI,and the distribution of cerebral infarction in both groups was analyzed,and the correlation between the location of cerebral infarction and the occurrence of PSD was analyzed.[Results]The proportion of infarction in the frontotemporal and parietal cortex,occipital cortex,brainstem and cerebellum in the PSD group was significantly higher than that in the PSND group,the difference was statistically significant (P occipital cortex > left frontal polar distance > multiple infarction > hippocampal amygdala > left frontal lobe > posterior part> right frontal lobe> right frontal polar distance> coronal area> anterior part of brain> basal nucleus area.[Conclu-sion]When the cerebral infarction is located in the brain stem and cerebellum and the frontotemporal parietal and occipital cortex with smaller left frontal pole distance,it is easy to appear early PSD,and the early PSD is related to the location of the infarct.