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目的 :通过检测胃粘膜相关淋巴组织 (MALT)淋巴瘤中的幽门螺杆菌 (HP) ,探讨HP与胃粘膜相关淋巴组织淋巴瘤的关系。方法 :收集 2 6例胃MALT淋巴瘤、2 0例淋巴性胃炎与 3 0例轻度浅表性胃炎的胃粘膜组织病理石蜡切片行 0 2 5 %甲苯胺蓝染色 ,显微镜检查HP。结果 :胃MALT淋巴瘤组、淋巴细胞性胃炎组及轻度浅表性胃炎组的HP感染率分别为 88 48%、65 0 0 %、43 3 3 % ,经统计学分析 ,差异有显著性 (P <0 0 5 )。结论 :HP感染与胃MALT淋巴瘤的发生有密切的关系 ,建议在对胃MALT淋巴瘤行化疗的同时行根除HP治疗
Objective: To investigate the relationship between HP and gastric mucosa-associated lymphoid tissue lymphoma by detecting Helicobacter pylori (HP) in gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Methods: Twenty-six cases of gastric MALT lymphoma, 20 cases of lymphatic gastritis and 30 cases of mild superficial gastritis were collected. The pathological paraffin sections were stained with 0 2 5% toluidine blue and examined by microscopy. Results: The HP infection rates in gastric MALT lymphoma group, lymphocytic gastritis group and mild superficial gastritis group were 88 48%, 65 0 0% and 43 3 3%, respectively, and the difference was statistically significant (P <0 05). Conclusion: HP infection is closely related to the occurrence of gastric MALT lymphoma. It is suggested that concurrent chemotherapy with eradication of HP in gastric MALT lymphoma