在伪彩色图像中我们可以看到,一只小鼠心脏中的外膜细胞(绿色,如图)围绕在小血管周围(红色)密封血管以防渗漏。用抗癌药物舒尼替尼(sunitinib)处理后,清除了小鼠心脏周围的外膜细胞(如图)。化疗产生的心脏损伤可能源于血管的渗漏。舒尼替尼是大家熟悉的一种抗癌药物,它会清除密封血管外的细胞而损伤心肌组织,Amgen生物技术公司的Vishnu Chin-talgattu及同事将这一结果在线报道于2013-05-29的《科学转化医学》(Science Transla- In the pseudo-color image we can see that the adventitial cells (green, as shown) in the heart of a mouse seal the blood vessels around the small blood vessels (red) to prevent leakage. After treatment with the anti-cancer drug sunitinib, the adventitial cells surrounding the mouse heart were removed (Figure). Cardiac damage caused by chemotherapy may result from vascular leakage. Sunitinib is a well-known anti-cancer drug that will remove myocardial cells that seal off extravascular cells and Vishnu Chin-talgattu and colleagues at Amgen Biotechnology Inc. reported the results online 2013-05-29 Science Transla-