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本文报告用~3H-TdR掺入法测定本室的NC系正常裸小鼠和荷人脑胶质瘤裸小鼠(NHG-1)的脾淋巴细胞转化功能。结果提示:正常的纯合子(nu/nu)T细胞缺乏,B细胞功能均正常;杂合子(nu/+)的T和B细胞功能均正常;荷瘤鼠(NHG-1,30代)除了T细胞缺乏,B细胞功能亦受到抑制。
In this paper, we reported the use of ~3H-TdR incorporation method to determine the splenic lymphocyte transformation function in NC normal nude mice and human glioma bearing nude mice (NHG-1) in our laboratory. The results suggest that normal homozygous (nu/nu) T cells are deficient and B cell functions are normal; heterozygous (nu/+) T and B cell functions are normal; tumor-bearing mice (NHG-1, 30 generations) The lack of T cells, B cell function is also inhibited.