The reaction enthalpy of solid solid coordination reaction of 8 hoxine with zinc acetate is determined by solution calorimetry in an isoperibel reaction calorimeter. The calorimetric solvent is the solution of hydrochloric acid (4 mol·L+{-1}). According to the results, the value Δ -r H ++--m=-1.002 kJ·mol+{-1} Δ -f H ++--m(Zn(oxin)-2·H-2O)=-582.123 kJ·mol+{-1} are recommended. ; The reaction enthalpy of solid solid coordination reaction of 8 hoxine with zinc acetate is determined by solution calorimetry in an isoperibel reaction calorimeter. The calorimetric solvent is the solution of hydrochloric acid (4 mol·L + {- 1 } ). According to the results, the value Δ Δ - r H + +  - - m = -1.002 kJ · mol + {- 1 } Δ - f H + +  - - m (Zn (oxin) - 2 · H - 2O) = - 582.123 kJ · mol + {- 1 } are recommended. ;