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本文报道采用血小板存活时间检测,血小板在脾及肝被扣押的类型及血小板相关免疫球蛋白水平的方法,对19例确诊为自身免疫性血小板减少性紫癜病人,于强的松或脾切除治疗前后进行检测,以探讨上述治疗反应的机理。19例病人中,男性7例,女性12例。结果 12例接受强的松治疗者中有11例血小板数比治疗前上升3倍。治疗前后血小板的恢复、血小板的存活及脾与肝脏中血小板被清除的检查结果提示上述治疗的反应与血小板生成增多有关。用~(111)铟(In)标记血小板检测脾与肝脏中网状内皮细胞对血小板的消除情况,仅显示有轻微变化。有7例进行血小板相关
This article reports the detection of platelet survival time, platelet in the spleen and liver were seized type and platelet-associated immunoglobulin levels in 19 cases of patients diagnosed with autoimmune thrombocytopenic purpura in prednisone or splenectomy before and after treatment For testing to explore the mechanism of the above treatment response. 19 patients, 7 males and 12 females. Results Of the 12 patients receiving prednisone, 11 showed an increase in platelet count of 3-fold compared with that before treatment. The recovery of platelets before and after treatment, the survival of platelets and the clearance of platelets in the spleen and liver suggest that the response to these treatments is associated with increased platelet production. Platelets were detected by ~ (111) indium (In) labeled platelets and platelets were removed from the reticulocytes in the spleen and liver to show only slight changes. There are 7 cases of platelet related