目的探讨急性脑梗死患者血清同型半胱氨酸(homocysteine，Hey)、胱抑素C(cystatin C，Cys-C)水平的变化及临床意义。方法回顾性分析2013年01月~2014年09月我院收治的46例急性脑梗死患者血清同型半胱氨酸、胱抑素C检测结果，并与同期50例正常健康人作对比分析。结果急性脑梗死组血清Hcy与胱抑素C水平均显著高于对照组(<0.05)。结论血清同型半胱氨酸、胱抑素C与脑梗死的发生及发展密切相关，血清同型半胱氨酸与血清胱抑素C检测在急性脑梗死的诊断及预后判断中有较好的临床价值。“,”Objective To investigate serum homocysteine in patients with acute cerebral infarction (homocysteine, Hey), changes in cystatin C (cystatin C, Cys-C) levels and clinical significance. Methods A retrospective analysis of 46 patients with acute cerebral infarction serum homocysteine, Cystatin C test results in January 2013 ~2014 in September in our hospital, and for comparative analysis with the same period 50 cases of normal healthy people. Results Acute cerebral infarction and serum cystatin C Hcy levels were significantly higher (