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目的了解云南省德宏州少数民族村寨居民丙型肝炎病毒(HCV)感染状况及其影响因素。方法采用横断面研究方法,从德宏州整群抽样10个相邻的少数民族村寨,所有16岁及以上居民为研究对象,问卷调查收集社会人口学、性行为和吸毒行为信息,并采集外周静脉血检测HCV抗体。对研究对象的基本情况采用描述性分析,对分类计数变量关联性采用χ2检验,并应用logistic回归分析HCV感染的影响因素,P<0.05为差异有统计学意义。结果本项研究共有735人符合入选标准,参与应答者582人,占79.18%。其中男性306人,占52.58%;年龄16～56岁,平均(34.55±10.17)岁;景颇族364人,占62.54%;农民569人,占97.77%;已婚491人,占84.36%。543人有过性行为,占93.30%;109人吸毒,占18.73%。HCV抗体阳性25人,占4.30%。多因素logistic回归分析显示,景颇族HCV感染风险高于其他民族(OR=3.69,95%CI:1.03～13.14),吸毒者HCV感染风险高于非吸毒者(OR=3.58,95%CI:1.17～10.97)。结论云南省德宏州少数民族村寨居民特别是景颇族、吸毒者HCV感染率较高,有必要加强HCV防控。
Objective To understand the status of hepatitis C virus (HCV) infection among ethnic minority villages in Dehong Prefecture of Yunnan Province and its influencing factors. Methods A cross-sectional study was conducted to investigate the demographic, sexual and behavioral data of 10 ethnic minority villages sampled from 10 neighboring ethnic minority villages in Dehong prefecture, and all residents aged 16 and over. The questionnaires were collected from the population, Venous blood was tested for HCV antibodies. The descriptive analysis of the basic situation of the study object, the classification of variables associated with χ2 test, and the use of logistic regression analysis of the impact of HCV infection, P <0.05 for the difference was statistically significant. Results A total of 735 patients met the inclusion criteria and 582 respondents (79.18%) were included in the study. 306 males, accounting for 52.58%; aged 16 to 56 years, with an average of (34.55 ± 10.17) years; Jingpo 364 people, accounting for 62.54%; farmers 569, accounting for 97.77%; married 491, accounting for 84.36%. 543 people had sex, accounting for 93.30%; 109 people drugged, accounting for 18.73%. HCV antibody positive 25 people, accounting for 4.30%. Multivariate logistic regression analysis showed that the risk of HCV infection in Jingpo was higher than that in other ethnic groups (OR = 3.69, 95% CI: 1.03-13.14). The HCV infection risk among drug addicts was higher than that of non-drug addicts (OR = 3.58, 95% CI: 1.17 ~ 10.97). Conclusion Residents of ethnic minority villages in Dehong Prefecture, Yunnan Province, especially Jingpo people, have a higher HCV infection rate and need to strengthen HCV prevention and control.