奎尼丁晕厥一词系 Selzer 于1964年提出,但实际上奎尼丁引起的室性心动过速一心室颤动而导致阿—斯综合征的发作早己有报告,为奎尼丁治疗中出现的最严重的毒性反应,常导致猝死,且其发生难以预测,而使奎尼丁临床应用受到一定的限制。如何早期识别和预防奎尼丁晕厥是具有重要临床意义的研究课题。晚近研究认为奎尼丁晕厥属于复极延缓综合征,通常以心电图的 QT 间期延长作为复极延缓的主要指标。本文通过分析我院房颤复律过程中发生奎尼丁晕厥或猝死的13例患者的临床和心电图资料并与109例房颤患者的183例次电复律用奎尼丁配合治疗而未发生晕厥的患者 Quinidine Syncope word Selzer proposed in 1964, but in fact Quinidine induced ventricular tachycardia and ventricular fibrillation led to the onset of Alzheimer’s disease has long been reported for the treatment of quinidine occurred The most serious toxic reactions, often lead to sudden death, and its occurrence is unpredictable, leaving the clinical application of quinidine is subject to certain restrictions. How to early identify and prevent quinidine syncope is an important clinical research topic. Recent studies suggest that Quinidine syncope belongs to repolarization retarded syndrome, ECG QT interval is usually prolonged as the main indicator of repolarization delay. In this paper, by analyzing the clinical and electrocardiographic data of 13 patients with quinidine syncope or sudden death in the course of AF during cardioversion in our hospital, we did not cooperate with 183 patients with electro-cardioversion of quinidine in 109 patients with atrial fibrillation Syncope in patients