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芳香酶催化雌激素而生成的雌激素是绝经后妇女雌激素产生的主要来源.芳香酶抑制剂通过抑制芳香化反应来降低雌激素,从而成为治疗激素依赖性乳腺癌的二线药物.
The aromatase-catalyzed production of estrogen by estrogens is the main source of estrogen production in postmenopausal women. Aromatase inhibitors reduce estrogen by inhibiting the aromatization reaction and thus become second-line drugs for the treatment of hormone-dependent breast cancer.