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[目的]探讨经导管肝动脉化疗栓塞术(TACE)对原发性肝癌患者生活质量的影响。[方法]对2007年8月至2010年8月35例原发性肝癌住院患者在TACE术前、术后分别用SF-36量表进行生活质量问卷调查。[结果]原发性肝癌患者治疗前各维度评分均显著低于正常组(P<0.01),TACE术后除躯体疼痛(P=0.054)、心理健康(P=0.082)、精力(P=0.060)外,躯体健康(P=0.000)、躯体角色功能(P=0.002)、社会功能(P=0.007)、情绪角色功能(P=0.001)和总体健康(P=0.005)5个维度评分均显著高于术前,但TACE术后各维度评分均低于正常对照组。[结论]原发性肝癌患者生理健康和精神健康均受到明显损害,TACE术有利于改善患者近期部分生活质量。
[Objective] To investigate the effect of transcatheter hepatic arterial chemoembolization (TACE) on quality of life in patients with primary liver cancer. [Methods] From August 2007 to August 2010, 35 hospitalized patients with primary hepatocellular carcinoma were surveyed with SF-36 quality of life questionnaire before and after TACE. [Results] The scores of all dimensions of HCC before treatment were significantly lower than those of normal group (P <0.01). After TACE, physical pain (P = 0.054), mental health (P = 0.082) (P = 0.000), body function (P = 0.002), social function (P = 0.007), emotional function (P = 0.001) and general health (P = 0.005) Higher than preoperative, but the scores of all dimensions after TACE were lower than the normal control group. [Conclusion] The physical and mental health of patients with primary liver cancer are significantly impaired. TACE is helpful to improve the quality of life of some patients in the near future.