Cancer stem cells(CSCs)are a relatively rare subpopulation of tumor cell with self-renewal and tumorigenesis capabilities.CSCs are associated with cancer recurrence,progression,and chemoradiotherapy resistance.Establishing a reliable platform for CSC enri
Objective:Hepatocyte nuclear factor 4α (HNF4A) has been demonstrated to be an oncogene in gastric cancer (GC). However, the roles of different HNF4A isoforms d
Objective:This phase 3 study aimed to test equivalence in efficacy and safety for QL1101,a bevacizumab analogue in Chinese patients with untreated locally advanced non-squamous non-small cell lung cancer(NSCLC).Methods:Eligible patients were randomly assi
Objective:Anlotinib is a novel tyrosine kinase inhibitor blocking angiogenesis.This study was performed to assess the efficacy and safety of anlotinib in patients with metastatic breast cancer.Methods:Patients with HER2-negative breast cancer,who were pre
Objective: The oncoprotein, hepatitis B X-interacting protein (HBXIP), has been reported to play an important role in human malignancies. However, its functions
Objective: To assess the efficacy and safety of the novel histone deacetylase inhibitor, chidamide, in combination with cyclophosphamide, doxorubicin, vincristi
Objective: Vascular endothelial growth factor (VEGF), apart from its predominant roles in angiogenesis, can enhance cancer cell proliferation, but its mechanism
目的:了解新冠肺炎疫情对口腔专科医院住院患者药品使用的影响。方法:采用回顾性统计方法,对比分析2019年和2020年本院住院患者药品、国家基本药物、抗菌药物、重点监控药品等的销售情况,以及住院患者药品销售金额前20位的变化。结果:2019年和2020年,住院患者药品销售金额分别为1946.29万元和1334.02万元。其中,国家基本药物销售金额占比分别为33.06%和32.16%,抗菌药物销售金额占比分别为14.08%和15.36%,重点监控药品销售金额占比分别为1.55%和0.78%。2019~2020
Objective:To establish a new classification of biliary tumor thrombus(BTT).Methods:Overall survival of patients with BTT was first used to determine whether it correlated with current hepatocellular carcinoma staging systems.Univariate and multivariate an
目的:提升门诊咨询药师相关理论知识和技术水平,促进药学服务的同质化和标准化。方法:以生殖相关用药咨询为例建立工作组和流程,通过问卷了解药师开展生殖相关咨询的现状,收集临床问题,基于疾病诊疗特点和咨询情况形成临床问题,参考药品说明书和临床指南并结合临床经验,制定标准化指引手册。结果:按照既定流程组成工作组,结合临床证据及专家经验整理成文。结论:从生殖用药咨询问题入手,加强用药咨询与临床科室的合作交流与协作方式,配合临床做好患者用药指导,形成生殖用药相关咨询工作流程和标准,有助于进一步提高药学服务质量,更好地