chidamide相关论文
目的 研究在Chidamide抑制乳腺癌MDA-MB-231细胞生长中,LncRNA ENST00000448869.1靶向调控Nestin对细胞生长的影响.方法 以人乳腺......
Chidamide combined with cyclophosphamide,doxorubicin,vincristine and prednisone in previously untrea
Objective:Chidamide is an oral histone deacetylase subtype-selective inhibitor approved for relapsed or refractory perip......
Objective To detect the expression status of ATM in T lymphoblastic lymphoma.To testify the tumor suppressor function of......
The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral
Objective:To assess the efficacy and safety of the novel histone deacetylase inhibitor,chidamide,in combination with cyc......
西达本胺是全球首个口服的亚型选择性组蛋白去乙酰化酶（HDAC）抑制剂，属于全新抗肿瘤作用机制的表观遗传调控剂类药物，被批准用于复发难......
The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral
Objective: To assess the efficacy and safety of the novel histone deacetylase inhibitor, chidamide, in combination with ......
Exploratory clinical study of chidamide, an oral subtype-selective histone deacetylase inhibitor, in
Objective:The recurrence or progression under endocrine therapy in hormone receptor-positive (HR+)advanced breast cancer......
目的回顾性分析髓系白血病接受异体造血干细胞移植患者的预后相关因素。病例方法205例接受异体造血干细胞移植(allo-HSCT)治疗患者......
A phase Ⅰ trial of an oral subtype-selective histone deacetylase inhibitor, chidamide, in combinatio
Objective: This phase Ⅰ study was to evaluate safety, maximum tolerated dose, pharmacokinetics and preliminary antitumo......
Venetoclax in combination with chidamide and dexamethasone in relapsed/refractory primary plasma cel
BACKGROUND Conventional therapies for primary plasma cell leukemia(pPCL)are usually ineffective,with a short remission t......
Inhibitory Effect of Histone Deacetylase Inhibitor on the Proliferation of Leukemia Cells and Its An
The aim of this study was to explore the inhibitory effect of histone deacetylase inhibitor (HDACI) on the proliferation......
目的:探讨混合表型白血病的有效诊断及诊治现状。方法:对1例混合表型白血病患者的诊治过程及方法作回顾性分析。结果:本例患者临床......
目的：通过研究组蛋白去乙酰化酶抑制剂西达本胺对Notch1、Sirt1基因表达的影响来探讨其对胃癌细胞株SGC-7901的体外抗增殖作用。方......
内分泌治疗是雌激素受体阳性乳腺癌的主要治疗手段,但耐药的发生限制了其应用,本研究目的为验证组蛋白去乙酰化酶抑制剂西达本胺是......
目的 探讨西达本胺对外周T细胞淋巴瘤(PTCL)的疗效和安全性。方法 2015年4月—2017年9月福建省肿瘤医院淋巴瘤头颈部肿瘤内科收治P......
目的：观察西达本胺对胰腺癌细胞BxPC-3和PANC-1生长抑制及诱导细胞凋亡作用，探讨西达本胺抗胰腺癌的机制。方法：西达本胺处理BxPC-3和......
目的：研究西达本胺对前列腺癌DUl45、PC3细胞生长抑制及凋亡调控的作用。方法：设置西达本胺浓度分别为4、8、16、32和64Ixmol／L的5个......
目的探讨西达本胺联合氟达拉滨治疗复发急性淋巴细胞白血病的疗效及安全性。方法根据随机数字表法将124例复发急性淋巴细胞白血病......
[Objectives] To analyze the dosage,curative effect,and adverse effect of Chidamide in treating peripheral T-cell lymphom......
Exploratory clinical study of chidamide, an oral subtype-selective histone deacetylase inhibitor, in
Objective:The recurrence or progression under endocrine therapy in hormone receptor-positive(HR+)advanced breast cancer(......
BACKGROUND Hepatosplenic T-cell lymphoma(HSTCL)is a rare subtype of non-Hodgkin’s lymphoma,which has an aggressive clin......
第一部分Chidamide下调AML SP1/NFκB/DNMT1、FLT3/STAT5表达及-其DNA去甲基化机制研究[目的l：研究HDAC抑制剂Chidamide对AML的抗白......
