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应用杀精子剂实行阴道避孕已有悠久的历史。早在上一世纪,Kolliker 就发现了一些有机药物有杀精子作用。此后,许多研究者对一系列的有机药物进行了筛选研究。截止1964年,国际计划生育联合会正式批准应用的外用杀精子剂就有二十三种。外用杀精子避孕药是由阴道用杀精子剂和惰性基质配伍而成。这种避孕方法的副作用小于口服避孕药,无全身性副反应,基本上无药物禁忌症,又不需要医生的特别指导和监督,因此,已成为常用的避孕措施之一。
The application of spermicide vaginal contraception has a long history. As early as the last century, Kolliker discovered that some organic drugs have a spermicidal effect. Since then, many researchers conducted a screening study on a series of organic drugs. As of 1964, there are 23 topical spermicides officially approved by the International Planned Parenthood Federation. Topical spermicide contraceptives by the vaginal spermicide and inert matrix compatibility made. This contraceptive method has fewer side effects than oral contraceptives, no systemic side effects, basically no drug contraindications, and no special guidance and supervision from a doctor. Therefore, it has become one of the commonly used contraceptive measures.