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肿瘤药物特别是长春新感所导致的支气管哮喘临床上极为少见,现报告1例如下.患者男,55岁,主因咳嗽,咳血痰2月加重伴声嘶20夭,于1993年2月25日入院.患者于1993年1月出现不明原因咳嗽,咳痰,痰中带血,偶伴有右胸隐痛,入院前20天上述症状加重伴声嘶,来我院检查.入院查体:T36.5℃、Bp16.0/10.7kPa,一般情况尚可,皮肤粘膜无黄染无皮疹,全身浅表淋巴结未触及,心脏(一)右肺下叩浊,呼吸音弱,双肺未闻及干湿性罗音,腹平坦,肝脾未及,余无特殊.化验:WBC9.8×10~9/L,Hb161g/L,BuN6.3mmol/L,肝功正常,心电图正常.经胸片、CT、纤维支气管镜及病理活检确诊右肺小细胞未分化癌Ⅲ期.既往否认哮喘及药物过敏史.
Bronchial asthma caused by cancer drugs, especially the new sense of Changchun clinically extremely rare, is reported as follows 1. The patient male, 55 years old, mainly due to cough, hemoptysis sputum in February increased with hoarseness 20 yao, on February 25, 1993 Admitted to hospital in January 1993 patients with unexplained cough, sputum, bloody sputum, even with the right chest pain, 20 days before admission the above symptoms aggravated with hoarseness, to our hospital examination. 5 ℃, Bp16.0 / 10.7kPa, the general situation is acceptable, skin and mucosa without yellow dye no rash, systemic superficial lymph nodes not touched, the heart (a) the right lung knock turbidity, weak breath sounds, both lungs did not smell and dry Wet rales, flat belly, liver and spleen, and no special test: WBC9.8 × 10 ~ 9 / L, Hb161g / L, BuN6.3mmol / L, normal liver function, normal electrocardiogram. CT, fibrobronchoscopy and pathological biopsy diagnosed right lung small cell undifferentiated carcinoma Ⅲ. Previously deny asthma and drug allergy history.