论文部分内容阅读
目的:探讨EGFR、VEGF和Ki-67的表达与乳腺癌的关系及判断预后的临床意义。方法:回顾性分析35例经病理确诊为乳腺癌患者的临床资料,测定其癌组织中的EGFR、VEGF、Ki-67表达。结果:EGFR、VEGF和Ki-67与乳腺癌临床分期、肿瘤大小、淋巴结转移数目均成正相关(P<0.05)。结论:在乳腺癌组织中,EGFR、VEGF、Ki-67各有不同的表达情况,三者可以作为判断乳腺癌预后并指导治疗的参考指标。
Objective: To investigate the relationship between the expression of EGFR, VEGF and Ki-67 and breast cancer and the clinical significance of prognosis. Methods: The clinical data of 35 patients with pathologically diagnosed breast cancer were retrospectively analyzed. The expressions of EGFR, VEGF and Ki-67 in the cancerous tissues were determined. Results: The expressions of EGFR, VEGF and Ki-67 were positively correlated with clinical stage, tumor size and lymph node metastasis (P <0.05). Conclusion: There are different expressions of EGFR, VEGF and Ki-67 in breast cancer tissues, which can be used as a reference index to judge the prognosis of breast cancer and to guide the treatment.