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安胃片又名204胃药,中国药典1977年版一部已收载。《中国药典》在本品的制法中,没有规定用何种润滑剂,但沈阳药学院编《常用药物制剂》(辽宁人民出版社,1975、1979)204胃药制法中,系选用硬脂酸镁(0.5%左右)作润滑剂。根据我们的生产实践证明:本品选用硬脂酸镁作润滑剂,会使产品崩解时限不合格。为了证明此点,我们对本厂和外厂加用硬脂酸镁生产的本品5个批号的产品,按《中国药典》方法,进行了崩解度时限的测定,结果均不合格,都在60分钟以上。
Anwei tablets, also known as 204 stomach medicine, Chinese Pharmacopoeia 1977 edition has been included. “Chinese Pharmacopoeia” in the system of law, there is no provision for what kind of lubricant, but the Shenyang Institute of Pharmacy “commonly used drugs” (Liaoning People’s Publishing House, 1975,1979) 204 stomach medicine system, the Department of the selection of hard Magnesium stearate (about 0.5%) as a lubricant. According to our production practice proved: This product is selected magnesium stearate as a lubricant, will make the product disintegration deadline. In order to prove this point, we add 5 batch products of this product produced by magnesium stearate to our factory and outside plant. According to the method of “Chinese Pharmacopoeia”, the disintegration time limit was determined and the results were unqualified. 60 minutes or more.