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代谢综合征(metabolic syndrome)曾以多种名称被描述,如代谢障碍综合征 X、胰岛素抵抗综合征,甚或更加奇特的名称如高甘油三酯血症-腰综合征(hypertriglyceridaemic waist syndrome)。这些名称常被交替使用,但它们所描述的临床特征并不完全相同。胰岛素抵抗综合征(insulin resistance syndrome,IRS)的概念由Reaven 在其划时代的 Banting 医学奖演讲中统一并扩展,IRS 最初的意义仅为教学用语,它把表面上看来并无关联的一大类生物学事件统一到一个病理生理学的概念范畴内。IRS 的概念涵盖了胰岛素抵抗个体中常见的大部分临床特征和代谢异常,与 IRS 相关的综合征包括2型糖尿病、心血管疾病、高血压、多囊卵巢综合征、非酒精性脂肪肝病、癌症、阻塞性睡眠呼吸暂停和肥胖(在 Reaven 最初的 IRS 概念中并未包括)。相
Metabolic syndrome has been described under various names such as Metabolic Disorder Syndrome X, Insulin Resistance Syndrome, or even more exotic names such as hypertriglyceridaemic waist syndrome. These names are often used interchangeably, but the clinical features they describe are not exactly the same. The notion of insulin resistance syndrome (IRS) has been reunified and expanded by Reaven in his landmark Banting Medical Awards presentation. The initial meaning of IRS was merely teaching and learning. It introduced a seemingly unrelated category Biological events unify into a pathophysiology concept. The concept of IRS covers most of the clinical and metabolic abnormalities common in insulin-resistant individuals and the syndromes associated with IRS include type 2 diabetes, cardiovascular disease, hypertension, polycystic ovary syndrome, non-alcoholic fatty liver disease, cancer , Obstructive sleep apnea and obesity (not included in the original IRS concept of Reaven). phase