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作者随机采集了年龄在28～38岁的5位健康女性和3位健康男性的外周血,作爆式红系形成单位(BFU-E)培养,并观察17-β雌二醇、黄体酮和前列腺素E_1(PGE_1)在体外对BFU-E 生长的影响。连续观察8周,发现女性外周血BFU-E 数变化大,而男性无显著变化;女性的差异与月经周期有关,月经周期开始时,BFU-E 数非常低,在第14天达高峰。BFU-E 培养的同时,作血清17-β雌二醇、黄体酮浓度检测,可见雌激素水平最高时BFU-E 数也最高,但血清激素水平与BFU-E 数无关。体外实验发现,17-β雌二醇
The authors randomly collected peripheral blood from 5 healthy women and 3 healthy men aged 28-38 years for BFU-E and observed the effects of 17-beta estradiol, progesterone and Effect of Prostaglandin E_1 (PGE_1) on the Growth of BFU-E in. After 8 weeks of continuous observation, it was found that the number of BFU-E in the peripheral blood of the female had a great change but no significant change in the male. The difference of the female was related to the menstrual cycle. The BFU-E number was very low at the beginning of the menstrual cycle and reached its peak on the 14th day. BFU-E cultured at the same time, serum 17-beta estradiol, progesterone concentration test shows that the highest estrogen levels BFU-E number is also the highest, but serum hormone levels and BFU-E number has nothing to do. In vitro experiments found that, 17-β-estradiol