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急性视网膜坏死是一组综合征,它包括:虹膜炎,玻璃体炎和血管闭塞性坏死性视网膜炎。作者对54例早期、单眼急性视网膜坏死患者进行了研究,其中31例用无环鸟苷治疗,另外23例未用此药治疗。在治疗组的31例中27例在12个月内另一只眼没有发病,占87.1%,而在未用无环鸟苷治疗组的23例患者中仅有7例另一眼没有发病,占30.4%。在一眼得病后的2年内,用无环鸟苷治疗的患者,另一眼免于发病的比例为75.3%,而未用无环鸟苷治疗的患者仅占35.1%。所以通过两组发病率的分析表明,无环鸟苷的治疗可以降低已患有急性视网膜坏死的病人另一眼患病的发病率。
Acute retinal necrosis is a group of syndromes that include: iritis, vitritis and vascular occlusive necrotizing retinitis. The authors studied 54 patients with early, monocular acute retinal necrosis, of whom 31 were treated with acyclovir and the other 23 were not treated with this drug. Of the 31 patients in the treatment group, 27 had no disease in the other eye at 12 months, accounting for 87.1%, whereas only 7 of 23 patients without acyclovir treated had no other disease, accounting for 30.4%. In the first 2 years after the onset of illness, patients treated with acyclovir had a 75.3% incidence of disease-free incidence in the other eye, compared to 35.1% of patients treated with acyclovir alone. Therefore, analysis of the incidence of the two groups shows that acyclovir treatment can reduce the incidence of other diseases in patients already suffering from acute retinal necrosis.