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血友病甲治疗面临着一个问题,是选择高纯度因子Ⅷ(FⅧ)浓制剂还是中纯度FⅧ浓制剂?这两种制剂有效性是一致的,但安全性有争议.传统使用的中纯度FⅧ浓制剂的比活性为1～50U/mg.而用单克隆抗体(McAb)亲和层析纯化的FⅧ浓制剂比活性
A problem with hemophilia A treatment is the choice of high purity factor Ⅷ (F Ⅷ) concentrates or medium purity F Ⅷ concentrates? The effectiveness of these two formulations is consistent, but the safety is controversial. The traditional use of the purity F Ⅷ The specific activity of the concentrated preparation is 1 ~ 50U / mg while the specific activity of the FⅧ concentrated preparation purified by the monoclonal antibody (McAb) affinity chromatography