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过敏性紫癜性肾炎属变态反应性疾病,是一种易复发较难治愈的疾病。单纯用西药或中药疗效都不满意。我院近8年来对33例确诊为过敏性紫癜性肾炎患者采用强的松加雷公藤联合治疗。男15例,女18例,年龄8~48岁,病程3天~2年者。临床分急性肾炎型14例,肾病综合征12例,慢性肾炎型7例。疗法:强的松0.5~1mg/mg·d,早顿服,至紫癜、血尿等临床症状消失,尿红细胞、蛋白转阴,2~8周后按每周5mg减量,直至2.5~10mg/d作维持量,维持6~12个月。同时用雷公藤1mg/kg·d,分二至三次服,连服6~12个月。完全缓解23例,其中18例病情稳定已超过2年6个月可算
Allergic purpura nephritis is an allergic disease, is a recurrence difficult to cure diseases. Pure Western medicine or traditional Chinese medicine are not satisfied with the efficacy. Nearly 8 years in our hospital for 33 cases of allergic purpura nephritis diagnosed with prednisone and Tripterygium combined treatment. 15 males and 18 females, aged 8 to 48 years old, duration of 3 days to 2 years. Clinical sub-acute nephritis in 14 cases, nephrotic syndrome in 12 cases, 7 cases of chronic nephritis. Treatment: prednisone 0.5 ~ 1mg / mg · d, morning service, to purpura, hematuria and other clinical symptoms disappear, urinary red blood cells, protein negative, 2 to 8 weeks 5mg weekly reduction, until 2.5 ~ 10mg / d for the maintenance of volume, maintaining 6 to 12 months. At the same time with Tripterygium 1mg / kg · d, two to three times service, even for 6 to 12 months. Complete remission in 23 cases, of which 18 cases stable condition has more than 2 years 6 months can be considered