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目的评价三探头脱氧葡萄糖符合线路断层显像(FDGTHTC)诊断肺癌的准确性。方法对比观察109例肺部疾病患者行FDGTHTC检查的结果及其最终病理诊断,按病灶直径(>15cm、≤15cm)分别计算FDGTHTC诊断不同体积病灶的敏感性、特异性、准确性。结果病理检查显示,109例患者中86例为肺癌,23例为良性疾病。全组FDGTHTC的诊断敏感性、特异性、准确性分别为95%(82/86),74%(17/23),91%(99/109)。FDGTHTC诊断的敏感性、特异性、准确性,病灶直径≤15cm者分别为1/3,7/7,8/10,直径>15cm者分别为98%(81/83),63%(10/16),92%(91/99),其中FDGTHTC诊断前者的敏感性明显低于后者,两组间差异有统计学意义(Fisher精确概率法检验,P=0005)。结论FDGTHTC是诊断肺癌较为有用的检查手段,对直径≤15cm的病灶诊断价值较低。
Objective To evaluate the diagnostic accuracy of three-probe deoxyglucose conformal tomography (FDGTHTC) in the diagnosis of lung cancer. Methods The results of FDGTHTC examination and final pathological diagnosis of 109 patients with pulmonary diseases were compared. The sensitivity, specificity and accuracy of FDGTHTC in diagnosing different volume lesions were calculated respectively according to the diameters of lesions (> 15cm, ≤15cm). Results The pathological examination showed that 86 of 109 patients were lung cancer and 23 patients were benign disease. The diagnostic sensitivity, specificity and accuracy of FDGTHTC were 95% (82/86), 74% (17/23) and 91% (99/109) respectively. The sensitivity, specificity and accuracy of FDGTHTC were 98% (81/83) and 63% (10/83) respectively for those with diameter less than 15 cm and those with diameter> 16) and 92% (91/99), respectively. The sensitivity of FDGTHTC in diagnosing the former was significantly lower than that in the latter. There was a significant difference between the two groups (Fisher exact test, P = 0005). Conclusion FDGTHTC is a useful diagnostic tool for the diagnosis of lung cancer, and has a low diagnostic value for lesions ≤ 15 cm in diameter.