对１０８例肝硬化患者血清总胆固醇（ＣＨＯ）和甘油三酯（ＴＧ）的变化进行了检测，结果表明，肝硬化患者的血清总胆固醇水平较慢性迁延性肝炎组及正常对照组显著降低（Ｐ＜００１），而血清甘油三酯水平稍低，差异无显著性。血清总胆固醇和甘油三酯水平随着肝脏功能损害程度的加重而降低，且甘油三酯水平在肝脏功能损害时降低更明显。血清总胆固醇与血清白蛋白呈显著正相关，与血清总胆红素呈显著负相关。说明血清总胆固醇和甘油三酯能较准确地提示肝细胞的损害程度，判断肝硬化病情，估计预后 The changes of serum total cholesterol (CHO) and triglyceride (TG) in 108 patients with cirrhosis were detected. The results showed that the serum total cholesterol level in patients with cirrhosis was significantly lower than that in chronic persistent hepatitis group and normal control group (P <001), while the level of serum triglyceride is slightly lower, the difference was not significant. Serum total cholesterol and triglyceride levels decreased with the severity of liver dysfunction, and triglyceride levels decreased more markedly when liver function was impaired. Serum total cholesterol and serum albumin showed a significant positive correlation, and serum total bilirubin was significantly negatively correlated. Description of serum total cholesterol and triglycerides can prompt more accurately damage the degree of liver cells to determine the condition of cirrhosis, prognosis