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目的 研究异常妊娠结局妇女宫颈分泌物弓形虫 (TOX)、衣原体 (CT)、支原体 (UU)、巨细胞病毒 (HCMV)感染情况及其相互联系。藉以指导不育症的监测与治疗。方法 应用聚合酶链反应(PCR)技术分别对 16 6例异常妊娠结局妇女 (异常组 )和 3 3 6例妇科及产前就诊妇女 (对照组 )的宫颈分泌物进行TOX、CT、UU、HCMV检测。结果 异常组TOX、CT、UU、HCMV的检出阳性率分别为 :2 1.1%、3 3 .7%、42 .2 %与 2 5 .3 % ,与对照组比较差异有显著意义 (P <0 0 1)。异常组以反复流产为主 ,其流产次数随TOX、UU检出率的增高而增多。结论 TOX、CT、UU、HCMV是引起流产、死胎、胎畸的重要感染源 ,其中TOX、UU是主要病原体
Objective To study the infection and correlation of TOX, CT, UU and HCMV in women with abnormal pregnancy outcome. To guide the monitoring and treatment of infertility. Methods TOX, CT, UU, HCMV were detected by polymerase chain reaction (PCR) in 166 women with abnormal pregnancy outcomes (abnormal group) and 336 women with gynecological or prenatal care (control group) Detection. Results The positive rates of TOX, CT, UU and HCMV in the abnormal group were 21.1%, 33.7%, 42.2% and 25.3%, respectively, which were significantly different from those in the control group (P < 0 0 1). Abnormal group mainly repeated abortion, the number of abortion with TOX, UU detection rate increased. Conclusions TOX, CT, UU and HCMV are the main sources of infection of miscarriage, stillbirth and fetal malformations, of which TOX and UU are the major pathogens