结核病治疗中的类赫氏反应是一种青霉素治疗后加重反应,多在首剂青霉素后30min~4h发生,是因为大量菌体被青霉素杀灭后释放毒素所致,当青霉素剂量较大时容易发生。其表现为患者突然出现寒战、高热、头痛、全身痛、心率和呼吸加快,原有病症加重,部分患者出现体温骤降、四肢厥冷。一般持续30min~1h。因可诱发肺弥漫性出血,须高度重视。赫氏反应亦可发生于其他钩体敏感抗菌药物的治疗过程中。在结核 Hezburn reaction in tuberculosis treatment is a kind of aggravating reaction after penicillin treatment, and more occurs 30min ~ 4h after the first dose of penicillin, because a large number of bacteria are released by penicillin to release toxin, which is easy when penicillin is in large dosage occur. The performance of patients with sudden chills, fever, headache, generalized pain, heart rate and breathing speed up, the original illness aggravated, some patients appeared body temperature dip, extremities Jueleng. Generally lasts 30min ~ 1h. Due to diffuse pulmonary hemorrhage can be induced, we must attach great importance. Hirschsprung’s response can also occur during treatment of other leptospiral sensitive antimicrobials. In tuberculosis