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局部手术治疗作为一种传统治疗手段在早期直肠癌(T1)中的治疗地位重新为临床关注。经过准确术前病灶分期评估、严格手术适应证、制定合理的个体化综合治疗方案,局部切除术并不是一种过时的治疗手段,对于低风险的早期结直肠癌仍可作为首选方案。关于局部切除在治疗早期直肠癌的合理性评估研究中存在组间病例、病例选择、试验设计以及辅助/新辅助治疗等差异限制,仍需要良好的、前瞻性、随机对照性试验进行研究。
Local surgical treatment as a traditional treatment regimen in the treatment of early rectal cancer (T1) regained clinical attention. After accurate staging assessment of preoperative lesions, strict indications for surgery, the development of a rational individualized comprehensive treatment plan, the local excision is not an outdated treatment, for low-risk early colorectal cancer can still be regarded as the preferred option. There is still a need for good, prospective, randomized, controlled trials of the differences between groups in terms of case selection, case selection, trial design, and adjuvant / neoadjuvant therapy in the evaluation of the rationality of local excision in the treatment of early rectal cancer.