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缺铁性贫血在很多亚洲国家是一个常见病。作者调查了斯里兰卡两个种族年龄在22-55岁的女性患者,临床确诊缺铁性贫血(血红蛋白低于12g,血清铁低于100μg/dl)的110例住院病人为研究对象,同时住院的无贫血病人70例为对照组。贫血组平均血红蛋白为5.2g/dl±1.9SD,对照组为13.4g/dl±1.1SD。贫血组平均血清铁为62.0μg/dl±21.1SD,对照组为121μg/dl±14.1SD。在观察组的110例病人中55例有口腔粘膜改变,其中41例的舌有全部或部分发生萎缩改变。在本研究中随意选择贫血组43人,对照组25人在颊粘膜取直径5mm活检样品,在显微镜下测量上皮厚度及对1000个基底细胞中的有丝分裂细胞进行计数。
Iron deficiency anemia is a common disease in many Asian countries. The authors investigated 110 Sri Lankan women of ethnicity, aged 22-55, and 110 inpatients with clinically confirmed iron-deficiency anemia (hemoglobin less than 12 g and serum iron less than 100 μg / dl) 70 patients with anemia as control group. The mean hemoglobin in the anemia group was 5.2 g / dl ± 1.9 SD and that in the control group was 13.4 g / dl ± 1.1 SD. In the anemia group, the mean serum iron was 62.0 μg / dl ± 21.1 SD and that in the control group was 121 μg / dl ± 14.1 SD. In the observation group of 110 patients, 55 cases of oral mucosal changes, of which 41 cases of all or part of the tongue atrophy changes. In this study, 43 patients were randomly selected from the anemia group and 25 from the control group. The biopsies of 5 mm in diameter were collected on the buccal mucosa. The epithelial thickness was measured under a microscope and the number of mitotic cells in 1000 basal cells was counted.