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目的了解塌陷性肾小球病在中国汉族人群中的发生情况及临床病理特点。方法对１９９６年１月至１９９８年３月８３２例肾活检患者的血液生化学指标，肾活检穿刺标本的光镜、免疫荧光、透射电镜等病理学检查结果进行分析，对３例患者行ＨＩＶ病毒学检查。结果塌陷性肾小球病发生率占局灶节段性肾小球硬化的１７６％，病理改变、临床特征及预后与国外报道类似。结论塌陷性肾小球病具有特殊的临床病理特征，预后差，是一种值得重视的病理临床新概念。
Objective To understand the occurrence and clinicopathological features of collagenous glomerulopathy in Chinese Han population. Methods The blood biochemical indexes of 832 cases of renal biopsy from January 1996 to March 1998 were analyzed by light microscope, immunofluorescence and transmission electron microscopy. Three patients underwent HIV test School inspection. Results The incidence of collapsed glomerular disease accounted for 17.6% of focal segmental glomerulosclerosis. The pathological changes, clinical features and prognosis were similar to those reported abroad. Conclusion The collapse of glomerular disease has a special clinicopathological features, the prognosis is poor, is a new concept of pathology worthy of attention.