中枢神经系统常见的血管畸形性疾病有:动静脉畸形(AVM)、硬脑膜动静脉瘘(DAVF)、海绵状血管瘤(CM)。对于这些疾病的确切病因和发病过程尚有未知点。最近有一些国外学者对血管内皮细胞生长因子(VEGF)在这些疾病中的表达进行了研究,并认为VEGF在其发展过程中有相当的作用,现综述如下。1血管内皮细胞生长因子(VEGF) VEGF是血管生长因子的一种。最早,Folkman就提出缺血缺氧能诱使机体产生血管生长因子.血管生长因子的主要作用足促使新生血管的生成。而VEGF是目前认为作用 Vascular malformations common to the central nervous system are arteriovenous malformations (AVMs), dural arteriovenous fistulas (DAVFs), and cavernous hemangiomas (CMs). The exact etiology and pathogenesis of these diseases is unknown. Recently, some foreign scholars have studied the expression of vascular endothelial growth factor (VEGF) in these diseases and considered that VEGF plays an important role in its development. 1 vascular endothelial growth factor (VEGF) VEGF is a kind of vascular growth factor. At first, Folkman proposed that hypoxia and hypoxia induce the body to produce angiogenic growth factor, whose main function is to promote angiogenesis. And VEGF is currently considered a role