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作者报告2例Cowden病,这是一个在面部、口腔粘膜、前臂及手背发生丘疹和结节并伴有甲状腺,乳房、胃肠道及女性生殖器肿瘤的综合征。它和内脏恶性肿瘤有关,皮损的出现常先于乳房、甲状腺及女性生殖器肿瘤的发生。此病应为医生所重视,因为对于这些皮损的识别,可以早期诊断内脏的肿瘤。
The authors reported two cases of Cowden’s disease, a syndrome of papules and nodules on the face, oral mucosa, forearm, and back of the hand with thyroid, breast, gastrointestinal, and female genital tumors. It is associated with visceral malignancy. The appearance of skin lesions often precedes the occurrence of breast, thyroid and female genital tumors. The doctor should pay attention to this disease because it can be used to early diagnose visceral tumors.