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目的:探讨分析小儿不完全川崎病(IKD)的早期诊断标准及临床特征,分析误诊、漏诊的原因,旨在为早期诊断与治疗此病、防止患儿冠状动脉病变(CAL)的发生提供可靠的理论依据。方法:选取2006年1月~2012年1月间我科收治的小儿不完全川崎病患儿40例作为研究对象,并将其临床资料进行回顾性的分析。结果:这40例患儿的临床表现不典型,且呈多样性,由于此病早期临床特征较少,因此误诊、漏诊率较高。本组40例患儿均伴有发热的症状,有5例患儿发生冠状动脉病变。结论:小儿不完全川崎病的早期临床特征较少,极易导致误诊、漏诊的发生,严重者可引发冠状动脉病变。因此,提高对小儿不完全川崎病的认识,及时对疑似病患进行相应的实验室检查是早期诊断该病的关键。尽早对该病患儿进行免疫球蛋白治疗,是减少及防止其发生冠状动脉病变的重要环节。
Objective: To investigate the early diagnosis criteria and clinical features of incomplete Kawasaki disease (IKD) in children and to analyze the causes of misdiagnosis and missed diagnosis so as to provide early diagnosis and treatment of the disease and prevent the occurrence of coronary artery disease (CAL) in children The theoretical basis. Methods: Forty children with incomplete Kawasaki disease admitted to our department from January 2006 to January 2012 were selected as the study subjects, and their clinical data were retrospectively analyzed. Results: The clinical manifestations of these 40 cases were not typical and varied. Due to the lack of early clinical features, the misdiagnosis and missed diagnosis rates were higher. The group of 40 children were accompanied by fever symptoms, coronary heart disease in 5 cases. Conclusion: The early clinical features of incomplete Kawasaki disease in infants are rare, which can easily lead to misdiagnosis and missed diagnosis. In severe cases, coronary artery disease can be induced. Therefore, to improve awareness of incomplete Kawasaki disease in children, timely and suspected patients with the appropriate laboratory tests is the key to early diagnosis of the disease. As soon as possible immunoglobulin treatment of children with the disease, is to reduce and prevent the occurrence of coronary artery lesions an important part.