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目的:观察外路显微手术对家族性渗出性玻璃体视网膜病变合并孔源性视网膜脱离的疗效。方法:回顾性系列病例研究。分析郑州市第二人民医院2015年6月至2018年6月家族性渗出性玻璃体视网膜病变合并孔源性视网膜脱离50例(50眼)的临床资料，所有患者均行外路显微手术，术后随访12个月，观察和分析术后效果。结果:一次手术视网膜复位47例(94.00%)。未复位的3例中，进行玻璃体切除术后视网膜复位。术后最佳矫正视力手动～0.04者8例，0.05～0.25者27例，≥0.3者15例。≥0.3者的比例与术前比较，差异具有统计学意义(n χ2＝15.462，n P＝0.001)。无严重的手术并发症。n 结论:外路显微手术治疗家族性渗出性玻璃体视网膜病变合并孔源性视网膜脱离操作简单、安全、有效。“,”Objective:To observe the efficacy of external-route microsurgery for the treatment of familial exudative vitreoretinopathy with rhegmatogenous retinal detachment.Methods:This was a retrospective case series study.The clinical data of 50 eyes of 50 cases with familial exudative vitreoretinopathy with rhegmatogenous retinal detachment from Jun.2015 to Jun.2016 in Zhengzhou Second People’s Hospital were analyzed and all the cases underwent external-route microsurgery. The follow-up time was 12 months.The postoperative efficacy was observed and analyzed.Results:The retina was reattached successfully after once operation in 47 cases(94.00%). Three cases without retinal reattachment received vitrectomy and achieved retinal reattachment.The best corrected visual acuity was hand motion-0.04 in 8 cases, 0.05-0.25 in 27 cases and≥0.3 in 15 cases.The difference was statistically significant in rate of BCVA≥0.3(n χ2=15.462, n P=0.001). No serious complication occurred.n Conclusion:External-route microsurgery for the treatment of familial exudative vitreoretinopathy with rhegmatogenous retinal detachment is a simple, safe and effective therapy.