作者报道100例伴绒毛淋巴细胞的脾淋巴瘤(SLVL),并对其形态学、免疫学标记、临床特征以及治疗对预后的影响进行了回顾性分析。100例SLVL中,男40例,女60例,年龄35～91(中数70)岁,随访期6～203个月(中位40个月)。 结果 血液学特点:76例患者有脾肿大,经体检及CT未发现肝大及淋巴结肿大。Hb6～18g/dl,16例患者<10g/dl;血小板中位数181×10~9/L,15例患者<100×10~9/L;白细胞中位数3.5×10~9/L,5例<1×10~9/L;76例显示淋巴细胞绝对增多,4.3～150×10~9/L,24例 The authors reported 100 cases of splenic lymphoma (SLVL) with villous lymphocytes, and performed a retrospective analysis of their morphological, immunological markers, clinical features, and effects of treatment on prognosis. In 100 cases of SLVL, there were 40 males and 60 females, aged 35 to 91 (medium 70 years). The follow-up period was 6 to 203 months (median 40 months). Results Hematological features: Splenomegaly was found in 76 patients, and hepatomegaly and lymphadenopathy were not detected by physical examination and CT. Hb6 ~ 18g/dl, 16 patients <10g/dl; median platelet 181 × 10 ~ 9/L, 15 patients <100 × 10 ~ 9/L; median white blood cells 3.5 × 10 ~ 9/L, 5 cases <1×10~9/L; 76 cases showed absolute increase of lymphocytes, 4.3～150×10~9/L, 24 cases