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旨在分析行肝动脉灌注药物（ＴＡＩ）和栓塞（ＴＡＥ）治疗的原发性肝癌的预后因素，对适应证再评价，并提出一种科学简便的预测预后的方法。分别用单因素和多因素方法对９２例行介入治疗的原发性肝癌进行了回顾性统计分析。其中行单纯灌注药物（ＴＡＩ）者２７人；碘化油化疗栓塞（ＬｐＴＡＣＥ）者１９人；碘化油加明胶海绵化疗栓塞（ＬｐＧｓＴＡＣＥ）者４６人。结果：单因素分析从１９个变量中得出肿瘤类型、包膜、门脉瘤栓、Ｃｈｉｌｄｓ分级、Ｏｋｕｄａｓ分期、治疗方式６个因素是影响ＴＡＩ和ＴＡＥ治疗预后的显著因素。用Ｃｏｘ比例风险模型多因素分析显示仅有Ｏｋｕｄａｓ分期和治疗方式是影响预后的独立的重要因素。根据Ｃｏｘ最终模型方程，得到预后指数：ＰＩ＝０．００１３×Ｏｋｕｄａｓ分期－０．２４９６×治疗方式，当病人ＰＩ＜－０．５为预后良好，ＰＩ＞－０．５为预后差。结论：肝癌体积过大，无包膜，合并有门脉瘤栓，肝功能明显减损，进行ＴＡＩ或ＴＡＥ时要慎重。通过评价病人Ｏｋｕｄａｓ分期，结合治疗方式计算预后指数（ＰＩ），可以预测预后，试用于临床，起到选择病例，指导治疗的作用
The purpose of this study was to analyze the prognostic factors of hepatocellular carcinoma (HCC) treated with hepatic arterial infusion (TAI) and embolization (TAE), re-evaluate indications, and propose a scientific and simple method for predicting prognosis. Univariate and multivariate methods were used to retrospectively analyze 92 cases of primary liver cancer. Twenty-seven patients who underwent single-infusion drug (TAI); 19 patients who underwent chemiluminescence chemoembolization (LpTACE); 46 patients who received iodized oil plus gelatin sponge chemoembolization (LpGsTACE). RESULTS: Univariate analysis revealed that tumor types, capsules, portal vein tumor thrombus, Childs grade, Okudas stage, and treatment modalities were the significant factors affecting the prognosis of TAI and TAE from 19 variables. Multivariate analysis using the Cox proportional hazards model revealed that only Okudas stage and treatment modalities are independent and important factors affecting prognosis. According to Cox’s final model equation, the prognostic index was obtained: PI = 0.0013 × Okudas stage - 0.2496 × treatment, when the patient PI <-0.5 is a good prognosis, PI> -0.5 poor prognosis. Conclusions: The hepatocellular carcinoma is too bulky, without capsule, combined with portal vein thrombus, liver function impairment, and caution when performing TAI or TAE. By evaluating the patient’s Okudas stage and calculating the prognostic index (PI) in combination with the treatment method, the prognosis can be predicted, and the clinical trials can be used to select the cases and guide the treatment.