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目的:分析阿昔洛韦序贯神经阻滞法在恶性肿瘤患者放化疗期间并发带状疱疹中的治疗效果。方法:选取43例进行恶性肿瘤放、化疗期间并发带状疱疹的患者为研究对象,随机分为观察组20例,先常规给予阿昔洛韦750 mg,1次/d,静脉滴注,连用7 d,外用炉甘石洗剂涂擦至疱疹消失,序贯用神经阻滞,1次/周,连续3周。对照组23例,常规抗病毒治疗后,继续口服甲钴胺、维生素B1等药物。结果:观察组患者临床症状缓解时间及疱疹消退时间较对照组缩短,引起神经痛后遗症较对照组减少,分别为15%(3/20)、52.17%(11/23)。结论:对恶性肿瘤并发带状疱疹患者应有足够的认识,早期序贯应用神经阻滞法,可减少后遗神经痛给患者生活带来的影响和对生命的威胁。
Objective: To analyze the therapeutic effect of acyclovir sequential nerve block in the treatment of patients with malignant tumor complicated with shingles during radiotherapy and chemotherapy. Methods: Forty-three patients with shingles during radiotherapy and chemotherapy of malignant tumor were randomly divided into observation group (n = 20) and routinely given acyclovir 750 mg once a day for intravenous infusion 7 d, topical calamine lotion rubbed to disappear herpes, sequential use of nerve block, 1 / week for 3 weeks. Control group, 23 cases of conventional antiviral therapy, continue oral mecobalamin, vitamin B1 and other drugs. Results: The relief time of clinical symptoms and herpes regression in the observation group were shorter than those in the control group. The sequelae of neuropathic pain were decreased in 15% (3/20) and 52.17% (11/23), respectively. Conclusion: Patients with malignant tumor complicated with shingles should have enough understanding of the early sequential application of nerve block method can reduce the impact of post-natal neuralgia on patients with life-threatening and life-threatening.