顺铂作为一种细胞毒类化疗药物可以增强放疗的作用,原因在于顺铂在细胞的DNA 中产生作用,当组织缺氧情况下则更为明显。临床治疗中根据其投药剂量与给药时间与放疗二者之间的关系可以为协同作用或相加作用的增强因素,其主要机理是放 Cisplatin, as a cytotoxic chemotherapeutic drug, can enhance the effect of radiotherapy because cisplatin exerts its effect on the DNA of the cell and is more pronounced when the tissue is hypoxic. In clinical treatment, the relationship between the dose and the time of administration and radiotherapy may be a synergistic or additive effect. The main mechanism is to