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目的:观察分析苍砂白芥汤与米非司酮联合对子宫肌瘤患者肌瘤体积和血清FSH、LH、E_2水平的影响。方法:选取2013年3月至2016年7月于本院接受治疗的124例子宫肌瘤患者,将所选患者按随机数字表法分为治疗组与对照组,每组各62例,对照组患者从月经来潮第1天开始口服米非司酮,治疗组患者在对照组患者基础上加上苍砂白芥汤联合治疗。回顾性分析两组患者的临床资料,对比分析两组患者治疗前后子宫肌瘤体积及血清促卵泡生成素(FSH)、黄体生成素(LH)、雌二醇(E_2)的水平情况。结果:治疗前,两组进行子宫肌瘤体积及FSH、LH、E_2水平的对比,两组不存在明显差异,差异无统计学意义(P>0.05);经治疗后,两组进行子宫肌瘤体积及FSH、LH、E_2水平的对比,两组存在明显差异,差异有统计学意义(P<0.05)。治疗组总有效率为96.77%,对照组总有效率为82.26%。两组进行治疗后总有效率对比存在明显差异,差异有统计学意义(P<0.05)。两组进行治疗后不良反应发生情况的对比不存在明显差异,差异无统计学意义(P>0.05)。结论:苍砂白芥汤与米非司酮联合治疗相比米非司酮单纯治疗,临床疗效更显著,能够明显改善患者临床体征,提高治疗安全性,有利于患者病情快速恢复,值得临床推广。
Objective: To observe and analyze the effects of Cinnamomum Saffron Decoction combined with mifepristone on fibroid volume, serum FSH, LH and E2 levels in patients with uterine fibroids. Methods: A total of 124 patients with uterine fibroids treated in our hospital from March 2013 to July 2016 were selected and randomly divided into treatment group and control group, with 62 patients in each group and control group Patients from the first day of menstrual cramps oral mifepristone, the treatment group patients in the control group plus Cinnamon White mustard soup combination therapy. The clinical data of two groups were retrospectively analyzed. The volume of uterine leiomyoma and the levels of serum FSH, LH and E2 were compared between the two groups before and after treatment. Results: Before treatment, the two groups of uterine fibroids volume and FSH, LH, E 2 levels, there was no significant difference between the two groups, the difference was not statistically significant (P> 0.05); after treatment, the two groups of uterine fibroids Volume and FSH, LH, E_2 levels of the two groups there was significant difference, the difference was statistically significant (P <0.05). The total effective rate was 96.77% in the treatment group and 82.26% in the control group. There was a significant difference between the two groups in total effective rate after treatment, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the incidence of adverse reactions after treatment, the difference was not statistically significant (P> 0.05). Conclusion: Compared with mifepristone alone, the combination of CABP and mifepristone is more effective than Mifepristone alone, which can significantly improve the clinical signs and improve the safety of treatment, which is beneficial to the rapid recovery of patients’ condition and worthy of clinical promotion .