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目的 应用定量组织速度成像和组织追踪法评价恢复期川崎病患儿左心功能状况。方法 恢复期川崎病患儿30例(患病组),正常儿童20例(正常组)。通过M型超声获得左室射血分数(LVEF),通过二尖瓣口血流频谱获得二尖瓣口血流快速充盈速度(E),左房收缩期速度(A),计算 E/A;应用定量组织速度成像和组织追踪分析软件测量心脏前间隔、后壁、前壁、下壁、后间隔和侧壁的二尖瓣环处收缩期峰值速度(Vs)、收缩期最大位移(D)、舒张早期峰值速度(Ve)、左房收缩期峰值速度(Va),计算Ve/Va。并比较两组间各参数。结果 患病组LVEF、E峰、A峰及E/A都在正常范围内,与正常组相比无统计学差异;各室壁的二尖瓣环处的Vs和D两组间差异有显著性意义,6个室壁的平均Vs和D两组间差异也有有显著性意义;各室壁的舒张速度Ve和Va以及Ve/Va,只在少数室壁两组间差异有显著性意义。结论 川崎病恢复期左室整体收缩功能受损,舒张功能尚正常;组织速度成像技术能够定量评价小儿纵向左室功能改变。
Objective To evaluate left ventricular function in children with convalescent Kawasaki disease by quantitative tissue velocity imaging and tissue tracking. Methods 30 patients with Kawasaki disease (sick group) and 20 normal children (normal group) were enrolled in this study. Left ventricular ejection fraction (LVEF) was obtained by M-mode ultrasound, mitral inflow velocity (E) and left atrial systolic velocity (A) The peak systolic velocity (Vs) and maximum systolic displacement (D) at mitral annulus of anterior heart, posterior wall, anterior wall, inferior wall, posterior septum and lateral wall were measured by quantitative tissue velocity imaging and tissue tracking software. , Peak early diastolic velocity (Ve), peak systolic velocity of left atrium (Va) and Ve / Va. And compare the parameters between the two groups. Results The LVEF, E peak, A peak and E / A in the diseased group were within the normal range, and there was no significant difference compared with the normal group. There was significant difference between the two groups in the mitral valve annulus The mean Vs and D of 6 walls were also significantly different between the two groups. The relaxation velocities Ve and Va and Ve / Va of each wall were significant only in the few walls. Conclusion In the recovery period of Kawasaki disease, left ventricular global systolic function is impaired and diastolic function is still normal. Tissue velocity imaging can quantitatively evaluate longitudinal left ventricular function in children.