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目的观察川芎嗪结合西药治疗癫痫的临床疗效。方法将158例患者随机分为治疗组(77例)和对照组(81例),对照组采用常规抗癫痫药物治疗,治疗组同时合用川芎嗪,两组疗程均为6个月;观察两组临床疗效及治疗后脑电图变化情况。结果治疗组和对照组总有效率分别为83.12%、67.90%,组间疗效有统计学意义(P<0.05);治疗组和对照组治疗后脑电图异常率分别为23.38%、38.27%,组间差异有统计学意义(P<0.05)。结论川芎嗪联合西药可以有效用于治疗癫痫,并可促进患者脑电图的恢复。
Objective To observe the clinical efficacy of tetramethylpyrazine combined with western medicine in the treatment of epilepsy. Methods 158 patients were randomly divided into treatment group (n = 77) and control group (n = 81). The control group was treated with conventional antiepileptic drugs. The treatment group was also treated with ligustrazine, and the two courses of treatment were both 6 months. Clinical Efficacy and EEG Changes After Treatment. Results The total effective rates of the treatment group and the control group were 83.12% and 67.90%, respectively, and there was significant difference between the two groups (P <0.05). The EEG abnormalities in the treatment group and the control group were 23.38% and 38.27% The difference was statistically significant (P <0.05). Conclusion Ligustrazine combined with western medicine can effectively treat epilepsy, and can promote the recovery of electroencephalogram in patients.