患儿,男,4个月。因咳嗽2周门诊以支气管肺炎收入院。患儿为 G_3P_3,孕35周早产,顺产,早产原因不详。孕期母亲体健。有2个姐姐,生长发育正常。父母为3代外近亲结婚。家族中无类似疾病史。入院查体:R36次/分,HR128次/分,体重6kg,头围41cm,身长72cm,营养发育欠佳,腹壁皮下脂肪薄,厚约0.3cm,反应正常。头颅形态欠佳,前额突出,前后径 Children, male, 4 months. 2 weeks due to cough clinics to bronchopneumonia income hospital. Children with G_3P_3, 35 weeks pregnant premature birth, spontaneous abortion, premature labor is unknown. Mother’s health during pregnancy. 2 sisters, growth and development of normal. 3 generations of parents outside the marriage of cousins. No similar family history of disease. Admission examination: R36 times / min, HR128 beats / min, weight 6kg, head circumference 41cm, length 72cm, poor nutrition, abdominal subcutaneous fat thin, about 0.3cm thick, the reaction was normal. Poor cranial shape, prominent forehead, anteroposterior diameter