论文部分内容阅读
以柴胡疏肝散加味的抗纤合剂具有清热解毒、疏肝解郁、利水活血,提高白蛋白的作用。研究抗纤合剂对SD大鼠DMN二甲硝胺模型的病理组织学、透明质酸及肝功能的影响。抗纤合剂能减轻DMN二甲硝胺模型的肝纤维化程度,降低血清透明质酸的浓度。抗纤合剂在DMN二甲硝胺模型的SD大鼠实验中抗大鼠肝纤维化有效,具有抗肝纤维化及降解胶原的作用。
The anti-fibrosis agent modified with Bupleurum Shugan San has the functions of clearing heat and detoxifying, relieving liver and relieving stagnation, promoting water and activating blood, and improving albumin. To study the effect of anti-fibrosis agent on the histopathology, hyaluronic acid and liver function of DMN-DMN model in SD rats. Anti-fibrosis agents can reduce the degree of hepatic fibrosis in the DMN-dimethylnitramine model and reduce serum hyaluronic acid concentrations. The anti-fibrosis agent is effective in anti-rat liver fibrosis in SD rat test of DMN-dimethylnitramine model, and has anti-hepatic fibrosis and collagen degradation effects.