本研究用放射自显影术对甲基苯并蒽(简称DMBA)诱发的地鼠颊囊上皮增生的细胞迁移进行了研究。结果表明,DMBA诱发的上皮增生的细胞迁移时间平均为40小时,较正常者(82小时)明显加快;有不全角化的区域细胞迁移更快(约24小时)。还提示DMBA诱发的上皮增生的细胞更新速度加快;不全角化时细胞增殖更活跃。 In this study, autoradiography was used to study the cell migration of hamster cheek pouch epithelial hyperplasia induced by methylbenzidine (abbreviated as DMBA). The results showed that the cell migration time of DMBA-induced epithelial hyperplasia averaged 40 hours, which was significantly faster than that of the normal (82 hours); the cells with incomplete keratinization migrated faster (about 24 hours). It also suggests that the rate of cell renewal accelerated by DMBA-induced epithelial hyperplasia; cell proliferation is more active when incompletely keratinized.