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目的探讨布托啡诺术后镇痛对行子宫肌瘤剔除术患者的影响。方法将68例患者随机分成试验组和对照组,其中试验组34例,采用布托啡诺镇痛方案;对照组34例,采用吗啡镇痛方案。观察和比较两组患者的镇痛效果、镇静程度、不良反应及患者的满意度。结果试验组患者术后各时段视觉模拟评分法(VAS)评分均略低于对照组,差异无统计学意义(P>0.05)。试验组患者术后各时段镇静评分(SS评分)均明显高于对照组,差异有统计学意义(P<0.05)。试验组患者的恶心呕吐、皮肤瘙痒等发生率明显低于对照组,差异有统计学意义(P<0.05)。试验组患者的总满意率明显高于对照组,差异有统计学意义(P<0.05)。结论布托啡诺应用于子宫肌瘤剔除术后镇痛效果良好,不良反应少,安全可靠。
Objective To investigate the effect of butorphanol on postoperative analgesia in patients undergoing myomectomy. Methods Sixty-eight patients were randomly divided into trial group and control group, 34 patients in trial group received butorphanol analgesia program and 34 patients in control group received morphine analgesia. The analgesic effect, sedation, adverse reactions and patient satisfaction were observed and compared between two groups. Results The visual analogue scale (VAS) scores of patients in trial group were slightly lower than those in control group at each time point after operation. The difference was not statistically significant (P> 0.05). The sedation score (SS score) in each experimental group after operation was significantly higher than that in the control group, with significant difference (P <0.05). The incidence of nausea, vomiting and pruritus in the test group was significantly lower than that in the control group (P <0.05). The total satisfaction rate of patients in experimental group was significantly higher than that in control group, the difference was statistically significant (P <0.05). Conclusion Butorphanol applied in the treatment of uterine fibroids analgesic effect is good, less adverse reactions, safe and reliable.