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目的探讨血清钠、胆碱酯酶水平与肝硬化患者病情严重程度的临床关系。方法随机选择120例肝硬化患者及100例体检健康者,检测其血清钠及血清胆碱酯酶水平,肝硬化患者按Child-Pugh分级标准分为A、B、C三级。结果肝硬化患者血清钠及血清胆碱酯酶水平均低于正常对照组(P<0.05),随肝功能Child分级,其异常程度逐级加重,差异有统计学意义(P<0.05/0.01),其下降值与肝硬化严重程度呈正相关,说明血清钠、胆碱酯酶水平对评估肝硬化严重程度有重要的指导意义。结论联合检测血清钙、胆碱酯酶,可作为判断肝硬化严重程度的指标,对判断预后起一定的指导作用。
Objective To investigate the clinical relationship between serum sodium and cholinesterase levels and the severity of liver cirrhosis. Methods A total of 120 patients with cirrhosis and 100 healthy subjects were randomly selected and their serum sodium and serum cholinesterase levels were measured. Patients with liver cirrhosis were divided into A, B and C levels according to Child-Pugh criteria. Results The levels of serum sodium and serum cholinesterase in patients with cirrhosis were significantly lower than those in normal control group (P <0.05). With the grading of liver function, the degree of abnormality increased step by step. The difference was statistically significant (P <0.05 / 0.01) , And its decline value is positively correlated with the severity of liver cirrhosis, indicating that serum sodium and cholinesterase levels have an important guiding significance for assessing the severity of liver cirrhosis. Conclusions Combined detection of serum calcium and cholinesterase can be used as an index to judge the severity of liver cirrhosis and play a guiding role in judging the prognosis.