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检测６１例高血压并脑梗塞、２９例单纯脑梗塞患者和２０名正常人的血糖（ＢＳ）、血浆胰岛素和促肾上腺皮质激素（ＡＣＴＨ），计算胰岛素敏感性指数，并与神经功能缺损评分和脑梗塞面积进行直线相关分析。结果：两组脑梗塞患者血浆胰岛素显著高于对照组（Ｐ＜０．０１）；胰岛素敏感性指数降低，与对照组比较均Ｐ＜０．０１。而ＢＳ、ＡＣＴＨ与对照组比较无显著差异。胰岛素敏感指数与神经功能缺损评分和梗塞面积呈负相关（ｒ＝－０．７１和－０．６４，Ｐ＜０．０１）。复查时血浆胰岛素水平虽有降低，但仍高于对照组。提示脑梗塞患者存在胰岛素抵抗，并可能为脑梗塞的一个独立危险因素
The blood glucose (BS), plasma insulin and adrenocorticotropic hormone (ACTH) in 61 patients with hypertension and cerebral infarction, 29 patients with simple cerebral infarction and 20 normal subjects were measured. Insulin sensitivity index was calculated and compared with neurological deficit score and Cerebral infarction area for linear correlation analysis. Results: The plasma insulin in both groups was significantly higher than that in the control group (P <0.01). The insulin sensitivity index was lower than that in the control group (P <0.01). The BS, ACTH compared with the control group no significant difference. Insulin sensitivity index was negatively correlated with neurological deficit scores and infarct size (r = -0.71 and -0.64, P <0.01). Review of plasma insulin levels although reduced, but still higher than the control group. Suggesting that there is insulin resistance in patients with cerebral infarction and may be an independent risk factor for cerebral infarction